diff --git a/pyproject.toml b/pyproject.toml
index dc3617f7fe..e4fc0b8e1f 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -42,7 +42,7 @@ classifiers = [
 ]
 dependencies = [
   "securesystemslib~=1.0",
-  "urllib3<3,>=1.21.1",
+  "urllib3~=2.0",
 ]
 dynamic = ["version"]
 
diff --git a/requirements/main.txt b/requirements/main.txt
index 611c6589d8..4d06f9e62d 100644
--- a/requirements/main.txt
+++ b/requirements/main.txt
@@ -7,4 +7,4 @@
 # triggers CI/CD builds to automatically test against updated dependencies.
 #
 securesystemslib[crypto]
-urllib3
+urllib3~=2.0